Оборвался прежний пост. Какой Нейтрум вопрос, где "между тем все интресно" вы мне задали, но на который я якобы "деликатно не отвечал"?
По лошадям: In horses, a mutation in the middle of the EDNRB gene, Ile118Lys, when homozygous, causes Lethal White Syndrome. Yang GC, Croaker D, Zhang AL, Manglick P, Cartmill T, Cass D (June 1998). "A dinucleotide mutation in the endothelin-B receptor gene is associated with lethal white foal syndrome (LWFS); a horse variant of Hirschsprung disease". Hum. Mol. Genet. 7 (6): 1047–52. doi:10.1093/hmg/7.6.1047. PMID 9580670. "sequence analysis, together with allele-specific PCR and the amplification-created restriction site (ACRS) technique, revealed a dinucleotide TC-->AG mutation, which changed isoleucine to lysine in the predicted first transmembrane domain of the EDNRB protein.